None of the reliable models bring Irma any further west than the Florida Panhandle, so the chance of Irma moving deeply into the central or western Gulf is increasingly remote.
In short, computer guidance is in strong agreement that Irma will make at least one landfall somewhere from Florida to North Carolina during the weekend or early next week. The official NHC forecast track as of 11 am Wednesday brings Irma from near Miami to near Daytona Beach from Sunday morning to Monday morning. Another model predicts that Irma will hit Miami on Sunday afternoon, then make a second landfall near the Georgia/South Carolina border on Monday afternoon, with both landfalls occurring with at least Category 4 strength.